»
Antibodies
»
anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) antibody
CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) antibody
| Antigen |
|
| Synonyms |
p50, Bp50, CDW40, MGC9013, TNFRSF5, IGM, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936, CD40 |
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
Flow Cytometry (FACS) (152), Immunoprecipitation (IP) (33), Immunohistochemistry (Frozen Sections) (IHC (fro)) (29), Western Blotting (WB) (29), ELISA (26), Functional Studies (Func) (18), Immunohistochemistry (IHC) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Enzyme Immunoassay (EIA) (8), Immunofluorescence (IF) (6), Blocking Antibody (Inhibition) (2), Immunocytochemistry (ICC) (2), Blocking Antibody (Inhibition) (1), ELISA (Detection) (1), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
|
| Catalog no. |
ABIN343486 |
| Quantity |
100ug |
| Price |
283.33 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Alternative name
|
CD40
|
|
Immunogen
|
A synthetic peptide corresponding to a sequence at the N-terminal of mouse CD40, identical to the related rat sequence.
|
|
Format
|
Affinity-purified
|
|
Isotype
|
IgG (Matching secondary antibodies)
|
|
Description
|
CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium .CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.
|
|
Specificity
|
Human, mouse, rat. No cross reactivity with other proteins.
|
|
Application Notes
|
Western blotting: At 1-2u/ml with the appropriate system to detect CD40 in cells and tissues. Other applications have not been tested. Optimal dilutions should be determined by end user.
|
|
Purity
|
Immunogen affinity purified.
|
|
Buffer
|
Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na 2 HPO 4 .
|
|
Storage
|
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 0.5ml of PBS is used, the antibody concentration will be 100ug/ml.
|
|
Research Area
|
Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis, Inflammation, Cancer
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40)", type "Antibodies"
|
Hosts
|
Mouse (111), Rat (60), Rabbit (19), Hamster (10)
|
|
Reactivities
|
Human (124), Mouse (Murine) (77), Rat (Rattus) (6), Chicken (4), Dog (Canine) (3), Monkey (3), Pig (Porcine) (2)
|
|
Applications
|
Flow Cytometry (FACS) (152), Immunoprecipitation (IP) (33), Immunohistochemistry (Frozen Sections) (IHC (fro)) (29), Western Blotting (WB) (29), ELISA (26), Functional Studies (Func) (18), Immunohistochemistry (IHC) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Enzyme Immunoassay (EIA) (8), Immunofluorescence (IF) (6), Blocking Antibody (Inhibition) (2), Immunocytochemistry (ICC) (2), Blocking Antibody (Inhibition) (1), ELISA (Detection) (1), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
|
|
Conjugates
|
FITC (29), Biotin (28), PE (23), APC (9), RPE (5), SPRD (3), Cy5,PE (2), Cy5.5,PE (2), Alexa Fluor 488 (1)
|
|
Epitopes
|
pThr254 (1)
|
Alternatives 
