Chorionic Gonadotropin(betalpha-Subunit) BetaHCG antibody

Antigen: Chorionic Gonadotropin(betalpha-Subunit) BetaHCG

Synonyms: CGB3, hCGB, CGB

Clonality: Monoclonal (HCG-8)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN343508

Additional Information

Immunogen: HCG Purification Purified by the goat anti-mouse IgG affinity chromatography.

Format: Affinity-purified

Isotype: IgG1  (Matching secondary antibodies)

Clone: HCG-8

Description: ß-HCG (ß-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain (CGB). It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, ß-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. ß-HCG is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. ß-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.

Specificity: Human. No cross reactivity with other proteins.

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Sections): At 0.25-0.5µg/ml to detect HCG in formalin fixed and paraffin embedded tissues. Other applications have not been tested. Optimal dilutions should be determined by end user.

Buffer: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative.

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml.

Restrictions: For Research Use only