Tyrosine Hydroxylase (TH) antibody

Antigen: Tyrosine Hydroxylase (TH)

Synonyms: TH, TyHyd, GB15303, th, LOC100219119, LOC446095, 2nd copy, Th, TYH, DYT14, DYT5b, The, DH65B, DTH, Pale, VII, dTH65B, pale/ple, DmelCG10118, CG10118

Clonality: Monoclonal (TH-100)

Host: Mouse

Reactivity: Human, Rat (Rattus), Rabbit

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Catalog no.: ABIN343519

Additional Information

Alternative name: Tyrosine Hydroxylase

Immunogen: Rat tyrosine hydroxylase(TH) Purification Purified by the goat anti-mouse IgG affinity chromatography.

Format: Affinity-purified

Isotype: IgG1  (Matching secondary antibodies)

Clone: TH-100

Description: Tyrosine hydroxylase is involved in the conversion of phenylalanine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Human TH gene contains 13 primary exons and spans approximately 8 kb. TH is in the 11p15.5 region

Specificity: Human, rat, rabbit. No cross reactivity with other proteins.

Application Details

Application Notes: Western blotting: At 0.25-0.5µg/ml with the appropriate system to detect tyrosine hydroxylase in cells and tissues. Immunohistochemistry (Paraffin-embedded Sections): At 0.5-1µg/ml to detect tyrosine hydroxylase in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F) At 0.5-1µg/ml to detect tyrosine hydroxylase in formalin or acetone fixed tissues. Other applications have not been tested. Optimal dilutions should be determined by end user.

Buffer: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative.

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml.

Research Area: Cancer, Amino Acids, Enzymes

Restrictions: For Research Use only