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Protein Kinase Ba antibody
| Antigen | Protein Kinase Ba |
| Clonality | Monoclonal (IML-26) |
| Host |
Mouse |
| Reactivity |
Human, Mouse (Murine), Rat (Rattus), Chicken |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN343534 |
| Quantity | 100ug |
| Price | 283.33 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Immunogen | Synthetic peptide corresponding to amino acids 461-477 of human PKBa/Akt1. Purification Purified by the goat anti-mouse IgG affinity chromatography. |
| Format | Affinity-purified |
| Isotype | IgG1 (Matching secondary antibodies) |
| Clone | IML-26 |
| Description | PKBaalso knows as V-AKT murine thymoma vial oncogene homolog 1(ATK1). AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. |
| Specificity | Human, mouse, rat, chicken. No cross reactivity with other proteins. |
Application Details
| Application Notes | Western blotting: At 0.25-0.5 µg/ml with the appropriate system to detect PKBa in cells and tissues. Other applications have not been tested. Optimal dilutions should be determined by end user. |
| Buffer | Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative. |
| Storage | At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml. |
| Restrictions | For Research Use only |
