Ornithine Decarboxylase 1 (ODC1) antibody

Antigen: Ornithine Decarboxylase 1 (ODC1)

Synonyms: ODC, MGC103389, Odc, dodc1, DmelCG8721, CG8721, odc, fc54f04, fi06d08, CHUNP6922, wu:fc54f04, wu:fi06d08, ODC1, odc1, odc1-A, MGC52612, xODC1, MGC69433

Clonality: Monoclonal (ODC-22)

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN343546

Additional Information

Alternative name: Ornithine Decarboxylase (ODC)

Immunogen: Recombinant mouse ornithine decarboxylase.

Format: Affinity-purified

Isotype: IgG2b  (Matching secondary antibodies)

Clone: ODC-22

Description: Ornithine decarboxylase (ODC), the first enzyme in polyamine synthesis, is a transcriptional target of MYC and a modifier of APC -dependent tumorigenesis. It is located to 2p25. There is considerable genetic homology between a region of mouse chromosome 12 and the distal short arm of human chromosome 2. Complete amino acid sequence of human ornithine decarboxylase deduced from complementary DNA.

Specificity: Human. No cross reactivity with other proteins.

Application Details

Application Notes: Western blotting: At 4 µg/ml with the appropriate system to detect ODC in cells and tissues. Immunohistochemistry (Paraffin-embedded Sections): At 8 µg/ml to detect ODC in formalin fixed and paraffin embedded tissues. Other applications have not been tested. Optimal dilutions should be determined by end user.

Concentration: 100 ug/ml

Purification: Purification Purified by the goat anti-mouse IgG affinity chromatography.

Buffer: PBS, 50% glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.

Research Area: Enzymes, Metabolism

Restrictions: For Research Use only