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Elastin (ELN) antibody

Antigen

Elastin (ELN)

Synonyms ELN, MGC148808, WS, WBS, SVAS, FLJ38671, FLJ43523, AI385707, AI480567, E030024M20Rik, Trela, TREL11, Trela26, RATTREL11
Clonality Monoclonal (IL-4)
Host
Reactivity
Alternatives

Human, Dog (Canine), Guinea Pig

Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Catalog no. ABIN343579
Quantity 100ug
Price 283.33 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Alternative name Elastin
Immunogen Bovine a-elastin Purification Purified by the goat anti-mouse IgG affinity chromatography.
Format Affinity-purified
Isotype IgG1
Clone IL-4
Description Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Defects in elastin are a cause of autosomal dominant cutis laxa.
Specificity Human, dog, guinea pig. No cross reactivity with other proteins.

Application Details

Application Notes Immunohistochemistry (Paraffin-embedded Sections): At 0.25-0.5 µg/ml to detect elastin in formalin fixed and paraffin embedded tissues. Other applications have not been tested. Optimal dilutions should be determined by end user.
Buffer Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative.
Storage At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml.
Research Area Cardiovascular, Extracellular Matrix
Restrictions For Research Use only