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Cdk7/CAK antibody
| Antigen | Cdk7/CAK |
| Clonality | Monoclonal (IMD-26) |
| Host | |
| Reactivity |
Human |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN343595 |
| Quantity | 100ug |
| Price | 283.33 $ Plus shipping costs $35.00 |
| Shipping to |
|
| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Immunogen | Recombinant human Cdk7 protein. Purification Purified by the goat anti-mouse IgG affinity chromatography. |
| Format | Affinity-purified |
| Isotype | IgG2b |
| Clone | IMD-26 |
| Description | CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7( CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent. |
| Specificity | Human. No cross reactivity with other proteins. |
Application Details
| Application Notes | Western blotting: At 0.25 µg/ml with the appropriate system to detect cdk7/cak in cells and tissues. Immunohistochemistry(F) At 0.5 µg/ml to detect cdk7/cak in formalin/acetone fixed tissues. Immunocytochemistry Suitable Other applications have not been tested. Optimal dilutions should be determined by end user. |
| Buffer | Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative. |
| Storage | At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml. |
| Restrictions | For Research Use only |
