CD4 Molecule (CD4) antibody

Antigen: CD4 Molecule (CD4)

Synonyms: CD4, MGC165891, cd4, CD4mut, L3T4, Ly-4, p55, W3/25

Clonality: Monoclonal (CA-4)

Host: Please enquire

Reactivity: Human, Rat (Rattus)

Catalog no.: ABIN343601

Additional Information

Alternative name: CD4

Immunogen: CD4-transfected mouse T-cell hybridoma, 3DT, followed by CD4+ human T-cell CEM cells. Purification Purified by the goat anti-mouse IgG affinity chromatography.

Format: Affinity-purified

Isotype: IgG1

Clone: CA-4

Description: CD stands for 'cluster of differentiation', the number that follows is arbitrarily assigned. In the full designation the cell type and nature and molecular weight of the antigen are given in brackets, for CD4, this is as follows: [T,gp55] .CD4 is present on a subset of T lymphocytes (helper/inducerT cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.

Specificity: Human, rat. No cross reactivity with other proteins.

Application Details

Application Notes: Immunohistochemistry(F) At 1 µg/ml to detect CD4 in formalin or acetone fixed tissues. Other applications have not been tested. Optimal dilutions should be determined by end user.

Buffer: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative.

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml.

Research Area: Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells

Restrictions: For Research Use only