BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibody

Antigen: BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1)

Synonyms: UCHL2, hucep-6, FLJ35406, FLJ37180, HUCEP-13, KIAA0272, DKFZp686N04275, IMP, BRAP2, RNF52, 3010002G07Rik, imp, MGC68778, zgc:92894, BRAP, MGC159981

Clonality: Monoclonal (BP-1)

Host: Please enquire

Reactivity: Human

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Catalog no.: ABIN343615

Additional Information

Alternative name: BAP1

Immunogen: Recombinant full-length BAP1. Purification Purified by the goat anti-mouse IgG affinity chromatography.

Format: Affinity-purified

Isotype: IgG1

Clone: BP-1

Description: BAP1, also knows as BRCA1-associated protein-1, contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals. BAP1 is a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. BAP1 is expressed as a 4-kb mRNA in all human tissues, and mapped to 3p21.3.

Specificity: Human. No cross reactivity with other proteins.

Application Details

Application Notes: Western blotting: At 0.5 µg/ml with the appropriate system to detect BAP1 in cells and tissues. Immunocytochemistry Suitable Other applications have not been tested. Optimal dilutions should be determined by end user.

Buffer: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.2mg NaN3 as preservative.

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml.

Restrictions: For Research Use only