Keratin 17 (KRT17) antibody
| Antigen |
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| Synonyms |
PC, K17, PC2, PCHC1, Krt1-17, MGC159887, Ka17, KRT17, krt16 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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Western Blotting (WB) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (30), Immunohistochemistry (Frozen Sections) (IHC (fro)) (18), Immunohistochemistry (IHC) (9), Immunofluorescence (IF) (6), Enzyme Immunoassay (EIA) (5), Immunocytochemistry (ICC) (4), ELISA (3), Flow Cytometry (FACS) (3), ELISA (Detection) (2), Immunoprecipitation (IP) (1)
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| Catalog no. |
ABIN343634 |
| Quantity |
100ul (0.5mg/ml) |
| Price |
350.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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CK17
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Swiss-Prot
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Q9QWL7
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Immunogen
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This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of mouse CK-17.
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Format
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Liquid
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Cytokeratin 17 may play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial stem cells. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation
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Application Notes
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Dilution: WB: 1:500-1,000. Positive Control: Hela. Cellular Localization: Cytoplasm. Molecular Weight: 48kDa.
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Concentration
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0.5mg/ml
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Purification
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Immunogen affinity purified
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Buffer
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1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
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Storage
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Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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Restrictions
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For Research Use only
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Alternatives for antigen "Keratin 17 (KRT17)", type "Antibodies"
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Hosts
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Mouse (25), Rabbit (16), Guinea Pig (1)
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Reactivities
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Human (36), Rat (Rattus) (11), Mouse (Murine) (3)
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Applications
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Western Blotting (WB) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (30), Immunohistochemistry (Frozen Sections) (IHC (fro)) (18), Immunohistochemistry (IHC) (9), Immunofluorescence (IF) (6), Enzyme Immunoassay (EIA) (5), Immunocytochemistry (ICC) (4), ELISA (3), Flow Cytometry (FACS) (3), ELISA (Detection) (2), Immunoprecipitation (IP) (1)
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Epitopes
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C-Term (5)
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Alternatives 
