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L1 Cell Adhesion Molecule (L1CAM) antibody

Antigen

L1 Cell Adhesion Molecule (L1CAM)

Synonyms S10, HSAS, MASA, MIC5, SPG1, CAML1, CD171, HSAS1, N-CAML1, l1cam-a, MGC80658
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Mouse (Murine), Rat (Rattus), Human

Application
Alternatives Western Blotting (WB), Immunocytochemistry (ICC)
Catalog no. ABIN343658
Quantity 100ul  (0.62mg/ml)
Price 350.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Alternative name NCAML1
Swiss-Prot P32004/P11627
Immunogen This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of C-terminal residues of NCAM-L1.
Format Liquid
Isotype IgG  (Matching secondary antibodies)
Description The neural cell adhesion molecule L1 (NCAM-L1) is an immunoglobulin superfamily adhesion molecule that is critical for neural development, involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Defects in L1CAM are the cause of hydrocephalus due to stenosis of the aqueduct of Sylvius (HSAS). Hydrocephalus is a condition in which abnormal accumulation of cerebrospinal fluid in the brain causes increased intracranial pressure inside the skull. Defects in L1CAM are also the cause of mental retardation, aphasia, shuffling gait, and adducted thumbs syndrome (MASA), a X-linked disorder.

Application Details

Application Notes Dilution: WB: 1:500-1,1000. Positive Control: Fetal brain. Cellular Localization: Cell Membrane. Molecular Weight: ~220kDa.
Concentration 0.62mg/ml
Purification Immunogen affinity purified
Buffer 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
Storage Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "L1 Cell Adhesion Molecule (L1CAM)", type "Antibodies"
Hosts Mouse (20), Rat (3), Goat (1), Rabbit (1)
Reactivities Human (22), Mouse (Murine) (4), Rat (Rattus) (1)
Applications Western Blotting (WB) (21), Immunoprecipitation (IP) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), Flow Cytometry (FACS) (6), ELISA (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), Enzyme Immunoassay (EIA) (2), Immunofluorescence (IF) (2), Immunocytochemistry (ICC) (1)
Conjugates Biotin (3), APC (1), PE (1)