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Amyloid beta (A4) Precursor Protein (APP) antibody

Antigen

Amyloid beta (A4) Precursor Protein (APP)
Synonyms APP, APP-like, APPL, Abeta, BcDNA:GH04413, EG:65F1.5, DmelCG7727, CG7727, AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, CTFgamma, aaa, ad1, pn2, abpp, appi, cvap, abeta, MGC88882, ctfgamma
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Mouse (Murine), Human, Rat (Rattus)
Application
Alternatives Western Blotting (WB)
Catalog no. ABIN343681
Quantity 100ul  (0.5mg/ml)  (Variants)
Price 350.00 $   Plus shipping costs $35.00
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Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Alternative name Amyloid Beta A4
Swiss-Prot P05067
Immunogen This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of APP.
Format Liquid
Isotype IgG  (Matching secondary antibodies)
Description Amyloid beta precursor protein (APP) is a 100-140 kDa transmembrane glycoprotein existing as several isoforms. The amino acid sequence of APP contains the amyloid domain (A-beta), which can be released by a two-step proteolytic cleavage. It is expressed in all fetal tissues examined with highest levels in brain, kidney, heart and spleen. APP acts as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is also involved in cell mobility and transcription regulation through protein-protein interactions.

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes Dilution: WB: 1:1,000. Positive Control: Hela. Cellular Localization: Cell membrane. Molecular Weight: ~110kDa.
Concentration 0.5mg/ml
Purification Immunogen affinity purified LT-alpha(Lymphotoxin-alpha)
Buffer 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
Storage Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Amyloid beta (A4) Precursor Protein (APP)", type "Antibodies"
Hosts Rabbit (133), Mouse (62), Goat (22)
Reactivities Human (168), Mouse (Murine) (55), Rat (Rattus) (36), Dog (Canine) (5), Monkey (5), Chicken (4), Cow (Bovine) (4), Pig (Porcine) (3), Guinea Pig (2), Rabbit (2), Primate (1)
Applications Western Blotting (WB) (188), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (55), ELISA (47), Enzyme Immunoassay (EIA) (47), Immunofluorescence (IF) (38), Immunohistochemistry (IHC) (36), Flow Cytometry (FACS) (18), Immunoprecipitation (IP) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (13), Dot Blot (Dot) (6), Immunocytochemistry (ICC) (3), Radioimmunoassay (RIA) (2)
Conjugates FITC (1)
Epitopes variant 1 (10), C-Term (9), N-Term (5), p668 (4), AA 653-662 (3), pThr668 (3), AA 292-312 (2), AA 44-63 (2), AA 671-685 (2), AA 747-761 (2), Ab-730 (2), pSer198 (2), pSer730 (2), pTyr756 (2), AA 1-14 (1), AA 350-450 (1), C-Term D672 (1), Carboxyl Terminal amino acids 737-751 (1), KPI Domain (1), Y756 (1), all isoforms (1), pS198 (1), pS730 (1), pThr743/668 (1)