NG & NG-NG-Methyl Arginine antibody

Antigen: NG & NG-NG-Methyl Arginine

Clonality: Monoclonal (Cov7E6)

Host: Mouse

Application: Western Blotting (WB)

Catalog no.: ABIN346794

Additional Information

Immunogen: Modified Methyl Arginine

Format: Ascites

Isotype: IgG1 kappa

Clone: Cov7E6

Specificity: Monoclonal antibody reacts with free and bound NG - NG - Dimethyl Arginine. Cross Reactivities: Cross reacts with free and bound NG - Monomethyl ArginineThere is no cross reaction with free or bound Arginine. Ability to fix complement : unknown

Application Details

Application Notes: Optimal dilutions should be determined by the end user. The following are guidelines only: Immunohistology : 1/100 to 1/10 000. Western Blot : 1/500 to 1/5 000

Buffer: Lyophilized from 100 µl of ascitic fluid. Preservative: None.

Storage: Short term storage: +4°C. Long term storage: -20°C

Restrictions: For Research Use only

Publications

Mowen, Tang, Zhu et al.: "Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription." in: Cell, Vol. 104, Issue 5, pp. 731-41, 2001 (PubMed).

Rho, Choi, Seong et al.: "The arginine-1493 residue in QRRGRTGR1493G motif IV of the hepatitis C virus NS3 helicase domain is essential for NS3 protein methylation by the protein arginine methyltransferase 1." in: Journal of virology, Vol. 75, Issue 17, pp. 8031-44, 2001 (PubMed).

Fabbrizio, El Messaoudi, Polanowska et al.: "Negative regulation of transcription by the type II arginine methyltransferase PRMT5." in: EMBO reports, Vol. 3, Issue 7, pp. 641-5, 2002 (PubMed).

Zhu, Mustelin, David: "Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase." in: The Journal of biological chemistry, Vol. 277, Issue 39, pp. 35787-90, 2002 (PubMed).

Li, Park, Kilburn et al.: "Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 44623-30, 2002 (PubMed).

Duong, Filipowicz, Tripodi et al.: "Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A." in: Gastroenterology, Vol. 126, Issue 1, pp. 263-77, 2003 (PubMed).