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Tubulin, Beta, 3 (TUBB3) antibody
| Antigen | Tubulin, Beta, 3 (TUBB3) |
| Synonyms | TUBB3, TUBB4, MGC134115, MC1R, beta-4, tbb3, M(beta)3, M(beta)6, 3200002H15Rik, tubb3, MGC76202, TUBB1, tubB3, tubulin |
| Clonality | Monoclonal (Tuj-1-TubIII-4G3) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blotting (WB)
|
 |
4 references available |
| Catalog no. | ABIN346893 |
| Quantity | 200 µl (Variants) |
| Price | 559.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 3 to 5 Business Days |
Additional Information
| Alternative name | Human class III beta-Tubulin |
| Immunogen | CIII beta-Tubulin protein (Cter domain) |
| Format | Ascites |
| Isotype | IgG1 kappa (Matching secondary antibodies) |
| Clone | Tuj-1-TubIII-4G3 |
| Specificity | Monoclonal antibody reacts specifically with human class III beta-Tubulin (55 kDa). Cross Reactivities: Not yet tested |
Application Details
| Application Notes | Optimal dilutions should be determined by the end user. The following are guidelines only: Immunocytochemistry : 1/100 to 1/500. Immunoprecipitation : 1/50 to 1/200. Western Blot : 1/200 to 1/1 000 |
| Buffer | Lyophilized from 200 µl of ascitic fluid. Preservative: None. |
| Storage | Short term storage: +4°C. Long term storage: -20°C |
| Restrictions | For Research Use only |
Publications
| Publications |
Sueve, Reiman, Lai et al.: "Class III beta-tubulin is a marker of paclitaxel resistance in carcinomas of unknown primary site." in: Cancer chemotherapy and pharmacology, Vol. 60, Issue 1, pp. 27-34, 2007 (PubMed).
Sueve, Dumontet: "Is class III beta-tubulin a predictive factor in patients receiving tubulin-binding agents?" in: The lancet oncology, Vol. 9, Issue 2, pp. 168-75, 2008 (PubMed). Vilmar, Santoni-Rugiu, Sørensen: "Class III {beta}-tubulin in advanced NSCLC of adenocarcinoma subtype predicts superior outcome in a randomized trial." in: Clinical cancer research : an official journal of the American Association for Cancer Research, 2011 (PubMed). (1:400, Sample species: Human). Further details: incubating for 20 min with the antibody (Clone TUJ- 14 1/TubIII/4G3) (diluted 1:400) against human TUBB3 Vilmar, Garcia-Foncillas, Huarriz et al.: "RT-PCR versus immunohistochemistry for correlation and quantification of ERCC1, BRCA1, TUBB3 and RRM1 in NSCLC." in: Lung cancer (Amsterdam, Netherlands), 2011 (PubMed). (1:400). |
Alternatives
Alternatives for antigen "Tubulin, Beta, 3 (TUBB3)", type "Antibodies"
| Hosts | Mouse (13), Rabbit (8), Chicken (1) |
| Reactivities | Human (14), Rat (Rattus) (6), Mouse (Murine) (4), Various Species (3), Chicken (2), All Species (1) |
| Applications | Western Blotting (WB) (18), Immunofluorescence (IF) (10), Enzyme Immunoassay (EIA) (4), Flow Cytometry (FACS) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), ELISA (3), Immunocytochemistry (ICC) (3), Immunohistochemistry (IHC) (3), ELISA (Detection) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunoprecipitation (IP) (1), Radioimmunoassay (RIA) (1) |
| Conjugates | Alexa Fluor 488 (1), Dyomics 547 (1), FITC (1) |
| Epitopes | pSer172 (1) |
