Purified antibody to Survival Motor Neuron (SMN) antibody

Antigen: Purified Antibody to Survival Motor Neuron (SMN)

Clonality: Monoclonal (CovSCB3)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB), ELISA

Catalog no.: ABIN346902

Additional Information

Immunogen: GST-SMN fusion protein

Format: Ascites

Isotype: IgG1 kappa  (Matching secondary antibodies)

Clone: CovSCB3

Specificity: Purified antibody reacts specifically with a 38-40 kDa protein in the various human foetal tissues tested. Cross Reactivities: Not yet tested

Application Details

Application Notes: Optimal dilutions should be determined by the end user. The following are guidelines only: Immunohistochemistry : 1/500 to 1/2 000-Immunoprecipîtation : 1/50 to 1/200-Western Blot: 1/500 to 1/2 000-ELISA: 1/1 000 to 1/5 000

Buffer: Lyophilized from 100 µl (25 µg) of purified antibody in PBS. Constituents: PBS. Preservative: Containing 0,02% sodium azide.

Storage: Short term storage: +4°C. Long term storage: -20°C

Restrictions: For Research Use only

Publications

Publications: Lefebvre, Buerglen, Reboullet et al.: "Identification and characterization of a spinal muscular atrophy-determining gene." in: Cell, Vol. 80, Issue 1, pp. 155-65, 1995 (PubMed).

Burlet, Huber, Bertrandy et al.: "The distribution of SMN protein complex in human fetal tissues and its alteration in spinal muscular atrophy." in: Human molecular genetics, Vol. 7, Issue 12, pp. 1927-33, 1998 (PubMed).