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Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody

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Antigen
Epitope
C-Term
(2)
Reactivity
Rat (Rattus)
(2)
Host
Rabbit
(1), (1)
Clonality
Polyclonal
Application
ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blotting (WB)
(2), (2), (2), (1), (1)
Pubmed 2 references available
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Quantity 200 μL
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Availability Will be delivered in 5 to 6 Business Days
Immunogen A 20 residue synthetic peptide derived from C-terminal domain of rat GLAST-1.
Isotype IgG
Specificity Reacts with rat 60 kDa EAAT1 protein. Cross react with mouse, human, chicken and zebrafish protein
Cross-Reactivity (Details) Reacts with rat 60 kDa EAAT1 protein. May cross react with mouse and human protein due to sequence homology.
Purification Antiserum
Background GLAST-1 is expressed in the central nervous system and is involved in L-glutamate and L- and D-aspartate transport.
Gene ID 29483
UniProt P24942
Application Notes Optimal dilution should be determined by the end user.
The following are guidelines only :
FC 1-10 - 1:200 IHC 1:50 - 1:500 WB 1:200 - 1:5 000
Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Storage -20 °C,4 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
Supplier Images
Image no. 1 for anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody (ABIN346977) anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody
Image no. 2 for anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody (ABIN346977) anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody (Image 2)
Product cited in: Nakajima, Kanamatsu, Takezawa et al.: "Up-regulation of glutamine synthesis in microglia activated with endotoxin." in: Neuroscience letters, Vol. 591C, pp. 99-104, 2015 (PubMed).

Background publications Rothstein, Dykes-Hoberg, Pardo et al.: "Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate." in: Neuron, Vol. 16, Issue 3, pp. 675-86, 1996 (PubMed).

Catalog No. ABIN346977
$464.80
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