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Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody

Details for Product No. ABIN346977, Supplier: Log in to see
Antigen
  • AF001784
  • AI504299
  • B430115D02Rik
  • CG3747
  • dEAAT
  • dEaat1
  • dEAAT1
  • Dglt-1
  • Dglut-1
  • Dmel\\CG3747
  • EA6
  • EAAT
  • Eaat1
  • EAAT1
  • GLAST
  • GLAST-1
  • GLAST1
  • GLU-T
  • GluT-1
  • Gmt1
  • MGluT1
  • slc1a3
  • SLC1A3
  • wu:fb98e05
  • wu:fd50b05
  • zgc:56661
  • zgc:77768
Epitope
C-Term
38
14
10
8
7
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Rat (Rattus)
75
45
30
14
Host
Rabbit
64
20
9
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
71
36
17
14
12
8
5
3
3
2
1
1
Supplier
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Immunogen A 20 residue synthetic peptide derived from C-terminal domain of rat GLAST-1.
Isotype IgG
Specificity Reacts with rat 60 kDa EAAT1 protein. Cross react with mouse, human, chicken and zebrafish protein
Purification Antiserum
Alternative Name Excitatory Amino Acid Transporter 1 (SLC1A3 Antibody Abstract)
Background GLAST-1 is expressed in the central nervous system and is involved inL-glutamate and L- and D-aspartate transport.

GLAST-1 | Sodium-dependent glutamate/aspartate transporter 1 Glial glutamate transporter Solute carrier family 1 member 3 Gene name: Slc1a3, Eaat1 Excitatory amino acid transporter 1
Gene ID 29483
UniProt P24942
Application Notes Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC(1-10 - 1:200) IHC(1:50 - 1:500) WB(1:200 - 1:5 000)
Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
Supplier Images
 image for anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody (ABIN346977) anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody
 image for anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody (ABIN346977) anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (C-Term) antibody (Image 2)
Product cited in: Nakajima, Kanamatsu, Takezawa, Kohsaka: "Up-regulation of glutamine synthesis in microglia activated with endotoxin." in: Neuroscience letters, Vol. 591C, pp. 99-104, 2015 (PubMed).

Background publications Rothstein, Dykes-Hoberg, Pardo, Bristol, Jin, Kuncl, Kanai, Hediger, Wang, Schielke, Welty: "Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate." in: Neuron, Vol. 16, Issue 3, pp. 675-86, 1996 (PubMed).

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