Peptidyl Arginine Deiminase, Type IV (PADI4) (C-Term) antibody

Details for Product No. ABIN347070
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Antigen
Synonyms PAD, PAD4, PADI5, PDI4, PDI5, Pad4, Pdi4
Epitope
C-Term
(13), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(61), (7), (7), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(44), (10), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(50), (21), (15), (11), (10), (9), (7), (5), (3), (1), (1), (1)
Pubmed 2 references available
Quantity 200 μL
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Catalog No. ABIN347070
519.49 $
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Immunogen A15 residue synthetic peptide derived from C-terminal domain of human PADI4 protein
Isotype IgG
Specificity Reacts with 74 kDa PADI4 protein from human, mouse and rat.
Cross-Reactivity (Details) Reacts with 74 kDa PADI4 protein from human, mouse and rat. No cross reaction with the other isoforms.
Purification Antiserum
Alternative Name Peptidylarginine Deiminase Type IV (PAD-4)
Application Notes Optimal dilution should be determined by the end user.
The following are guidelines only: ELISA: 1/1 000 to 1/5 000, IHC: 1/50 to 1/100, IP: 1/20 to 1/100, WB: 1/200 to 1/2 000
Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Concentration 1 mg/mL
Buffer Tris 0,1 M, glycine 0,1 M, sucrose 2 %
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20 °C. Store reconstituted antibodies at +4 °C. For extended periods store in aliquots at -20 °C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
General Nakashima, Hagiwara, Ishigami et al.: "Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3)." in: The Journal of biological chemistry, Vol. 274, Issue 39, pp. 27786-92, 1999 (PubMed).

Wang, Wysocka, Sayegh et al.: "Human PAD4 regulates histone arginine methylation levels via demethylimination." in: Science (New York, N.Y.), Vol. 306, Issue 5694, pp. 279-83, 2004 (PubMed).

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