Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody

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Synonyms 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, mKIAA1736, Nyw1, DCAF3, WDR94
(23), (19), (13), (5), (2), (1), (1), (1), (1)
Mouse (Murine)
(78), (47), (34), (1), (1)
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
(62), (36), (28), (20), (12), (6), (5), (4), (4), (1), (1)
Pubmed 4 references available
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Quantity 100 μL
Shipping to United States ( )
Availability Will be delivered in 5 to 6 Business Days
Immunogen Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.
Isotype IgG
Specificity Antiserum reacts specifically with 120 kDa of mouse protein.
Cross-Reactivity Rat (Rattus), Human
Cross-Reactivity (Details) Reacts with mouse 120 kDa Ambra1 protein. Cross reacts with human and rat protein.
Purification Antiserum
Alternative Name Activating molecule in Beclin 1-regulated autophagy (Ambra-1) (AMBRA1 Antibody Abstract)
UniProt Q9C0C7
Application Notes Optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Concentration 1 mg/mL
Buffer Tris 0,1 M, glycine 0,1 M, sucrose 2 %
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20 °C. Store reconstituted antibodies at +4 °C. For extended periods store in aliquots at -20 °C. Antibodies are guaranteed for 6 month from date of receipt.
Supplier Images
Image no. 1 for anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (ABIN347117) anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody
Product cited in: Van Humbeeck, Cornelissen, Hofkens et al.: "Parkin interacts with ambra1 to induce mitophagy." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10249-61, 2011 (PubMed).

Armstrong, Corazzari, Martin et al.: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, 2011 (PubMed).

Di Bartolomeo, Corazzari, Nazio et al.: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, 2010 (PubMed).

Background publications Fimia, Stoykova, Romagnoli et al.: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, 2007 (PubMed).

Catalog No. ABIN347117
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