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Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody

Details for Product No. ABIN347117
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Antigen
Synonyms Nyw1, 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, mKIAA1736, DCAF3, WDR94
Epitope
N-Term
(19), (10), (2), (2), (1), (1)
Reactivity
Mouse (Murine)
(51), (44), (29), (13), (12), (1)
Host
Rabbit
(57), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
(48), (31), (25), (14), (10), (6), (1), (1), (1), (1)
Pubmed 4 references available
Quantity 100 µL
Options
Shipping to United States (Change)
Availability Will be delivered in 5 to 6 Business Days
Catalog No. ABIN347117
353.32 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.
Isotype IgG
Specificity Antiserum reacts specifically with 120 kDa of mouse protein.
Cross-Reactivity Rat (Rattus), Human
Cross-Reactivity (Details) Reacts with mouse 120 kDa Ambra1 protein. Cross reacts with human and rat protein.
Purification Antiserum
Alternative Name Activating molecule in Beclin 1-regulated autophagy (Ambra-1)
UniProt Q9C0C7
Application Notes Optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Concentration 1 mg/mL
Buffer Tris 0,1 M, glycine 0,1 M, sucrose 2 %
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20 °C. Store reconstituted antibodies at +4 °C. For extended periods store in aliquots at -20 °C. Antibodies are guaranteed for 6 month from date of receipt.
Supplier Images
anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody
Product cited in: Di Bartolomeo, Corazzari, Nazio et al.: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, 2010 (PubMed).

Armstrong, Corazzari, Martin et al.: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, 2011 (PubMed).

Van Humbeeck, Cornelissen, Hofkens et al.: "Parkin interacts with ambra1 to induce mitophagy." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10249-61, 2011 (PubMed).

General Fimia, Stoykova, Romagnoli et al.: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, 2007 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN347117
353.32 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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