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Autophagy/beclin-1 Regulator 1 (AMBRA1) antibody

Antigen

Autophagy/beclin-1 Regulator 1 (AMBRA1)
Synonyms Ambra1, AA474864, AV021921, mKIAA1736, A130023A14, RP23-273F8.1, 2310079H06Rik, D030051N19Rik, DCAF3, WDR94, FLJ20294, KIAA1736, MGC33725, AMBRA1, MGC128737
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Mouse (Murine), Human, Rat (Rattus)
Application
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
4 references available
Catalog no. ABIN347117
Quantity 100 µl  (Variants)
Price 377.00 $   Plus shipping costs $35.00
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anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) antibody

Additional Information
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Alternative name Activating molecule in Beclin 1-regulated autophagy (Ambra-1)
Immunogen Synthetic peptide derived from N terminal region of mouse activating molecule in Beclin 1-regulated autophagy Ambra-1
Format Antiserum
Specificity Antiserum reacts specifically with 120 kDa of mouse protein. Cross Reactivities: Cross reacts with human and rat protein

Application Details
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Application Notes Optimal dilution should be determined by the end user. The following are guidelines only: Immunohistochemistry : 1/100 to 1/500. Western Blot : 1/500 to 1/2 000
Buffer Lyophilized from 100 µl of serum. Preservative: None.
Storage Short term storage: +4°C. Long term storage: -20°C
Research Area Autophagy
Restrictions For Research Use only

Publications
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Publications Fimia, Stoykova, Romagnoli et al.: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, 2007 (PubMed).

Di Bartolomeo, Corazzari, Nazio et al.: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, 2010 (PubMed).

Armstrong, Corazzari, Martin et al.: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, 2011 (PubMed).

Van Humbeeck, Cornelissen, Hofkens et al.: "Parkin interacts with ambra1 to induce mitophagy." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10249-61, 2011 (PubMed).

Alternatives
Application Details Publications Images Secondary Antibodies Variants back to top

Alternatives for antigen "Autophagy/beclin-1 Regulator 1 (AMBRA1)", type "Antibodies"
Hosts Rabbit (31)
Reactivities Human (28), Mouse (Murine) (23), Rat (Rattus) (21), Chicken (16), Dog (Canine) (16), Horse (Equine) (16), Rabbit (16), Cow (Bovine) (3), Pig (Porcine) (1)
Applications Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Western Blotting (WB) (14), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunohistochemistry (IHC) (5), ELISA (4), Enzyme Immunoassay (EIA) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes C-Term (3), N-Term (2), internal (2)