Autophagy/beclin-1 Regulator 1 (AMBRA1) antibody
| Antigen | Autophagy/beclin-1 Regulator 1 (AMBRA1) |
| Synonyms | Ambra1, AA474864, AV021921, mKIAA1736, A130023A14, RP23-273F8.1, 2310079H06Rik, D030051N19Rik, DCAF3, WDR94, FLJ20294, KIAA1736, MGC33725, AMBRA1, MGC128737 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Mouse (Murine), Human, Rat (Rattus) |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Immunohistochemistry (IHC), Western Blotting (WB) |
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4 references available |
| Catalog no. | ABIN347117 |
| Quantity | 100 µl (Variants) |
| Price | 423.98 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 5 to 6 Business Days |
Additional Information
| Alternative name | Activating molecule in Beclin 1-regulated autophagy (Ambra-1) |
| Immunogen | Synthetic peptide derived from N terminal region of mouse activating molecule in Beclin 1-regulated autophagy Ambra-1 |
| Format | Antiserum |
| Specificity | Antiserum reacts specifically with 120 kDa of mouse protein. Cross Reactivities: Cross reacts with human and rat protein |
Application Details
| Application Notes | Optimal dilution should be determined by the end user. The following are guidelines only: Immunohistochemistry : 1/100 to 1/500. Western Blot : 1/500 to 1/2 000 |
| Buffer | Lyophilized from 100 µl of serum. Preservative: None. |
| Storage | Short term storage: +4°C. Long term storage: -20°C |
| Research Area | Autophagy |
| Restrictions | For Research Use only |
Publications
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Fimia, Stoykova, Romagnoli et al.: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, 2007 (PubMed).
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| Product |
Di Bartolomeo, Corazzari, Nazio et al.: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, 2010 (PubMed).
Armstrong, Corazzari, Martin et al.: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, 2011 (PubMed). Van Humbeeck, Cornelissen, Hofkens et al.: "Parkin interacts with ambra1 to induce mitophagy." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10249-61, 2011 (PubMed). |
Alternatives
Alternatives for antigen "Autophagy/beclin-1 Regulator 1 (AMBRA1)", type "Antibodies"
| Hosts | Rabbit (44) |
| Reactivities | Human (41), Mouse (Murine) (33), Rat (Rattus) (29), Chicken (21), Dog (Canine) (20), Horse (Equine) (19), Cow (Bovine) (2), Cat (Feline) (1) |
| Applications | Western Blotting (WB) (28), ELISA (20), Immunofluorescence (IF) (19), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Immunohistochemistry (IHC) (7), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |
| Conjugates | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1) |
| Epitopes | N-Term (28), C-Term (4), AA 1-50 (1), Internal Region (1) |
