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AMBRA1 antibody (N-Term)

AMBRA1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN347117
  • Target See all AMBRA1 Antibodies
    AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))
    Binding Specificity
    • 21
    • 15
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 40
    • 28
    • 12
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 54
    • 1
    Rabbit
    Clonality
    • 54
    • 1
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AMBRA1 antibody is un-conjugated
    Application
    • 47
    • 13
    • 13
    • 13
    • 11
    • 10
    • 10
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    Specificity
    Reacts with mouse 120 kDa Ambra1 protein
    Cross-Reactivity
    Rat (Rattus)
    Cross-Reactivity (Details)
    Cross reacts with human and rat protein.
    Purification
    Antiserum
    Immunogen
    Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.
    Isotype
    IgG
    Top Product
    Discover our top product AMBRA1 Primary Antibody
  • Application Notes

    Working dilution: Optimal dilution should be determined by the end user.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Must be reconstituted in distilled water.
    Storage
    4 °C/-20 °C
    Storage Comment
    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    Expiry Date
    24 months
  • Armstrong, Corazzari, Martin, Pagliarini, Falasca, Hill, Ellis, Al Sabah, Redfern, Fimia, Piacentini, Lovat: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).

    Di Bartolomeo, Corazzari, Nazio, Oliverio, Lisi, Antonioli, Pagliarini, Matteoni, Fuoco, Giunta, DAmelio, Nardacci, Romagnoli, Piacentini, Cecconi, Fimia: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, (2010) (PubMed).

  • Target
    AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))
    Alternative Name
    Activating Molecule in BECN1-Regulated Autophagy Protein 1 (Ambra1) (AMBRA1 Products)
    Synonyms
    2310079H06Rik antibody, A130023A14 antibody, AA474864 antibody, AV021921 antibody, D030051N19Rik antibody, mKIAA1736 antibody, Nyw1 antibody, DCAF3 antibody, WDR94 antibody, autophagy and beclin 1 regulator 1 antibody, autophagy/beclin-1 regulator 1a antibody, autophagy/beclin 1 regulator 1 antibody, AMBRA1 antibody, ambra1a antibody, Ambra1 antibody
    Background
    Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation
    Gene ID
    55626
    UniProt
    Q9C0C7
    Pathways
    Autophagy
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