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Details for Product No. ABIN350007

Unc-51 Like Kinase 1 (C. Elegans) (ULK1) (Internal Region) antibody

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Antigen
Synonyms Unc51.1, AU041434, mKIAA0722, ATG1, ATG1A, UNC51, hATG1, ULK1, si:dkey-11o18.7, ulk1
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Human, Rat (Rattus), Mouse (Murine)
Host
»Alternatives Sheep
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 7 references available
Catalog no. ABIN350007
Quantity 150 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide as a part of human, rat, mouse serine/threonine-protein kinase ULK1 (ULK1, ATG1, UNC51, Unc51.1, KIAA0722) conjugated to immunogenic carrier protein has been used as the immunogen.
Specificity Appears to be specific for ULK1.
Purity whole serum
Alternative Name ULK1 (ATG1)
Background Function: Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells.
Catalytic activity: ATP + a protein = ADP + a phosphoprotein.
Subunit: Interacts with GABARAP and GABARAPL2. Also known as: Unc-51-like kinase 1, ATG1, UNC51, Unc51.1.
UniProt O75385
Research Area Autophagy
Application Notes IHC, WB. Use at a dilution of 1 : 200 to 1 : 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Kuroyanagi, Yan, Seki et al.: "Human ULK1, a novel serine/threonine kinase related to UNC-51 kinase of Caenorhabditis elegans: cDNA cloning, expression, and chromosomal assignment." in: Genomics, Vol. 51, Issue 1, pp. 76-85, 1998 (PubMed).

Okazaki, Yan, Yuasa et al.: "Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation." in: Brain research. Molecular brain research, Vol. 85, Issue 1-2, pp. 1-12, 2001 (PubMed).

Tomoda, Kim, Zhan et al.: "Role of Unc51.1 and its binding partners in CNS axon outgrowth." in: Genes & development, Vol. 18, Issue 5, pp. 541-58, 2004 (PubMed).

Young, Chan, Hu et al.: "Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes." in: Journal of cell science, Vol. 119, Issue Pt 18, pp. 3888-900, 2006 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Wissing, Jänsch, Nimtz et al.: "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 3, pp. 537-47, 2007 (PubMed).

Chan, Kir, Tooze: "siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy." in: The Journal of biological chemistry, Vol. 282, Issue 35, pp. 25464-74, 2007 (PubMed).

Alternatives for antigen "Unc-51 Like Kinase 1 (C. Elegans) (ULK1)", type "Antibodies"
Hosts (56), (4), (3)
Reactivities (61), (36), (32), (25), (13), (12), (3), (2), (1), (1), (1)
Applications (34), (20), (18), (15), (8), (8), (4), (3), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (16), (8), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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