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Trace Amine Associated Receptor 6 (TAAR6) antibody

Details for Product No. ABIN350016
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Antigen
Synonyms RP11-295F4.3, TA4, TAR4, TAR6, TRAR4, taR-4, taR-6, Gm228, Ta4
Reactivity
Rat (Rattus), Mouse (Murine)
(10)
Host
Chicken
(10)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(8), (2), (1)
Pubmed 4 references available
Quantity 100 µL
Options
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Availability Will be delivered in 7 to 8 Business Days
Catalog No. ABIN350016
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from mouse TAAR6 conjugated to an immunogenic carrier protein was used as the antigen.
Isotype IgY
Specificity Highly specific for mature olfactory neurons (including axon and terminals).
Purification whole serum
Alternative Name trace amine-associated receptor 6 (TAAR6, TaR-4)
Background Function: Orphan receptor. Could be a receptor fortrace amines.trace amines are biogenic amines present in very low levels in mammalian tissues. Although sometrace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.
Subcellular location: Cell membrane, Multi-pass membrane protein.
Tissue specificity: Expressed at low abundance in various brain tissues, as well as in fetal liver, but not in the cerebellum or placenta. In the brain, comparable levels of expression in basal ganglia, frontal cortex, substantia nigra, amygdala and hippocampus, highest expression in hippocampus and lowest expression in basal ganglia. Also known as:trace amine-associated receptor 6,trace amine receptor 4, TaR-4, TA4, TAR4, TRAR4, Ta4, Tar4, Trar4.
UniProt Q64288
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term.
Expiry Date 12 months
General Borowsky, Adham, Jones et al.: "Trace amines: identification of a family of mammalian G protein-coupled receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 8966-71, 2001 (PubMed).

Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Duan, Martinez, Sanders et al.: "Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia." in: American journal of human genetics, Vol. 75, Issue 4, pp. 624-38, 2004 (PubMed).

Lindemann, Ebeling, Kratochwil et al.: "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors." in: Genomics, Vol. 85, Issue 3, pp. 372-85, 2005 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN350016
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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