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Details for Product No. ABIN350019

Transmembrane Protein 166 (FAM176A) antibody

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Antigen
Reactivity
»Alternatives Human, Rat (Rattus), Mouse (Murine)
Host
»Alternatives Sheep
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350019
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from human transmembrane protein 166 (TM166, TMEM166) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen is homologous in rat and mouse.
Isotype IgG
Specificity Appears to be specific for TMEM166.
Purity IgG
Alternative Name transmembrane protein 166 (TM166, TMEM166)
Background Function: Acts as a regulator of programmed cell death, mediating bothautophagy and apoptosis.
Subcellular location: Endoplasmic reticulum membrane, Single-pass membrane protein. Lysosome membrane, Single-pass membrane protein.
Tissue specificity: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle. Also known as: TM166, TMEM166.
UniProt Q9H8M9
Research Area Autophagy
Application Notes IHC, WB. Use at a concentration of 10-50 µg/ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Wan, Gong, Qin et al.: "Large-scale cDNA transfection screening for genes related to cancer development and progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 44, pp. 15724-9, 2004 (PubMed).

Hillier, Graves, Fulton et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).

Wang, Yu, Lu et al.: "TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis." in: Apoptosis : an international journal on programmed cell death, Vol. 12, Issue 8, pp. 1489-502, 2007 (PubMed).

Alternatives for antigen "Transmembrane Protein 166 (FAM176A)", type "Antibodies"
Hosts (1), (1)
Reactivities (2), (2), (2)
Applications (2), (2)
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