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Transmembrane Protein 166 (FAM176A) antibody

Details for Product No. ABIN350019
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Antigen
Reactivity
Mouse (Murine)
(2)
Host
Rabbit
(2)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(2), (2)
Pubmed 4 references available
Quantity 500 µg
Options
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Catalog No. ABIN350019
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from human transmembrane protein 166 (TM166, TMEM166) conjugated to an immunogenic carrier protein has been used as the antigen. The peptide is homologous in rat and mouse.
Specificity Specific for MOR106-1 (see also the Immunogen).
Purification IgG
Alternative Name transmembrane protein 166 (TM166, TMEM166)
Background Function: Acts as a regulator of programmed cell death, mediating bothautophagy and apoptosis.
Subcellular location: Endoplasmic reticulum membrane, Single-pass membrane protein. Lysosome membrane, Single-pass membrane protein.
Tissue specificity: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle. Also known as: TM166, TMEM166.
UniProt Q9WU86
Application Notes Use at a concentration of 10-50 µg/mL.
The optimal working concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
General Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Wan, Gong, Qin et al.: "Large-scale cDNA transfection screening for genes related to cancer development and progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 44, pp. 15724-9, 2004 (PubMed).

Hillier, Graves, Fulton et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).

Wang, Yu, Lu et al.: "TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis." in: Apoptosis : an international journal on programmed cell death, Vol. 12, Issue 8, pp. 1489-502, 2007 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN350019
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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