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Details for Product No. ABIN350030

5HT1A Receptor (Serotonin Receptor 1A) (Cytoplasmic Domain) antibody

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Antigen
Epitope
»Alternatives Cytoplasmic Domain
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN350030
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 3d cytoplasmic domain of mouse 5HT1A receptor (Serotonin receptor 1A, Gpcr18, 5-hydroxytryptamine receptor 1A) conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 96% identity with rat and
Specificity Specific for CASR.
Purity whole serum
Background Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Most abundantly expressed in midbrain and cortex. Also known as: Serotonin receptor 1A, Gpcr18, 5-hydroxytryptamine receptor 1A, Htr1a.
UniProt Q9QY96
Research Area Receptors
Application Notes A dilution of 1: 300 to 1: 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Charest, Wainer, Albert: "Cloning and differentiation-induced expression of a murine serotonin1A receptor in a septal cell line." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 13, Issue 12, pp. 5164-71, 1994 (PubMed).

Wilkie, Chen, Gilbert et al.: "Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors." in: Genomics, Vol. 18, Issue 2, pp. 175-84, 1994 (PubMed).

Parks, Shenk: "The serotonin 1a receptor gene contains a TATA-less promoter that responds to MAZ and Sp1." in: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 4417-30, 1996 (PubMed).

Alternatives for antigen "5HT1A Receptor (Serotonin Receptor 1A)", type "Antibodies"
Hosts (1)
Reactivities (1), (1)
Applications (1), (1)
Epitopes (1)
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