Alstrom Syndrome 1 (ALMS1) (C-Term) antibody
| Antigen | Alstrom Syndrome 1 (ALMS1) |
| Synonyms | ALSS, KIAA0328, DKFZp686A118, DKFZp686D1828, bbb, ALMS1 |
| Binding Site |
Alternatives C-Term |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity | |
| Application |
Alternatives Immunohistochemistry (IHC), Western Blotting (WB) |
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5 references available |
| Catalog no. | ABIN350040 |
| Quantity | 100 µl |
| Price | 454.67 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 7 to 8 Business Days |
Additional Information
| Alternative name | Alstrom syndrome protein 1 homolog (ALMS1) |
| UniProt | P60880 |
| Immunogen | A synthetic peptide from C-terminal part of mouse Alstrom syndrome protein 1 homolog (ALMS1) conjugated to an immunogenic carrier protein was used as the immunogen. |
| Format | Lyophilized |
| Description | FUNCTION: Possible role in intracellular trafficking. SUBCELLULAR LOCATION: Cytoplasm. Centrosome. Cell projection, cilium basal body. Note: Associated with centrosomes and basal body at the base of primary cilia. During mitosis localizes to both spindle poles. TISSUE SPECIFICITY: Ubiquitously expressed. DEVELOPMENTAL STAGE: Expressed at E7.5. At E8.0 expression is found in mesodermal- and ectodermal-derived layers. At E10.5 mainly detected in midbrain, hindbrain, forelimb and hindlimb. Also expressed at E15.5 and E18.5. MISCELLANEOUS: Mice lacking Alms1 display obesity, hypogonadism, hyperinsulinemia, retinal dysfunction and hearing loss. Also known as: ALMS1. |
| Specificity | Appears to be specific for ALMS1. |
Application Details
| Application Notes | IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. |
| Purity | whole serum |
| Storage | Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Restrictions | For Research Use only |
Publications
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Collin, Marshall, Ikeda et al.: "Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alström syndrome." in: Nature genetics, Vol. 31, Issue 1, pp. 74-8, 2002 (PubMed).
Okazaki, F-Kikuno, Ohara et al.: "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 11, Issue 3, pp. 205-18, 2004 (PubMed). Collin, Cyr, Bronson et al.: "Alms1-disrupted mice recapitulate human Alström syndrome." in: Human molecular genetics, Vol. 14, Issue 16, pp. 2323-33, 2005 (PubMed). Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed). Dai, Jin, Sheng et al.: "Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry." in: Journal of proteome research, Vol. 6, Issue 1, pp. 250-62, 2007 (PubMed). |
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Alternatives
Alternatives for antigen "Alstrom Syndrome 1 (ALMS1)", type "Antibodies"
| Hosts | Goat (4), Rabbit (2) |
| Reactivities | Human (5), Cow (Bovine) (1), Dog (Canine) (1), Mouse (Murine) (1), Rat (Rattus) (1) |
| Applications | ELISA (4), Western Blotting (WB) (3), Immunohistochemistry (IHC) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1) |
| Epitopes | C-Term (1), Internal Region (1) |




Alternatives