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ALMS1 antibody (Alstrom Syndrome 1) (C-Term)

Details for Product anti-ALMS1 Antibody No. ABIN350040, Supplier: Login to see New
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Synonyms ALMS1, ALSS, bbb
(17), (5), (2), (1), (1), (1)
Mouse (Murine)
(34), (3), (3), (3), (3), (1), (1), (1)
(17), (17)
This ALMS1 antibody is un-conjugated
(1), (1), (1), (1), (1), (1)
Immunohistochemistry (IHC), Western Blotting (WB)
(22), (19), (16), (3), (2), (2), (2), (1), (1)
Pubmed 5 references available
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Quantity 100 μL
Shipping to United States ( )
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from C-terminal region of mouse Alstrom syndrome protein 1 homolog (ALMS1) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for ALMS1.
Purification Whole serum
Alternative Name ALMS1 (ALMS1 Antibody Abstract)
Background Function: Possible role in intracellular trafficking.
Subcellular location: Cytoplasm. Centrosome. Cell projection, cilium basal body. Note: Associated with centrosomes and basal body at the base of primary cilia. During mitosis localizes to both spindle poles.
Tissue specificity: Ubiquitously expressed.
Developmental stage: Expressed at E7.5. At E8.0 expression is found in mesodermal- and ectodermal-derived layers. At E10.5 mainly detected in midbrain, hindbrain, forelimb and hindlimb. Also expressed at E15.5 and E18.5.
Miscellaneous: Mice lacking Alms1 display obesity, hypogonadism, hyperinsulinemia, retinal dysfunction and hearing loss. Also known as: ALMS1.
Research Area Immunology
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Dai, Jin, Sheng et al.: "Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry." in: Journal of proteome research, Vol. 6, Issue 1, pp. 250-62, 2007 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome. ..." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Collin, Cyr, Bronson et al.: "Alms1-disrupted mice recapitulate human Alström syndrome." in: Human molecular genetics, Vol. 14, Issue 16, pp. 2323-33, 2005 (PubMed).

Okazaki, F-Kikuno, Ohara et al.: "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 11, Issue 3, pp. 205-18, 2004 (PubMed).

Collin, Marshall, Ikeda et al.: "Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alström syndrome." in: Nature genetics, Vol. 31, Issue 1, pp. 74-8, 2002 (PubMed).

Catalog No. ABIN350040
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