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AMRA1 (Internal Region) antibody

Reactivity: Human IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN350069
  • Target
    AMRA1
    Binding Specificity
    Internal Region
    Reactivity
    Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    Specific for AMBRA1.
    Cross-Reactivity
    Human, Mouse
    Cross-Reactivity (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogen
    A synthetic peptide from the internal region of human Activating molecule in BECN1 regulated autophagy protein 1 (AMBRA1, AMRA1) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen is homologous in mouse.
    Isotype
    IgG
  • Application Notes
    IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    AMRA1
    Background
    Function: Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Subcellular location: Cytoplasmic vesicle âÄ° autophagosome,Mammalian Autophagy,Activating molecule in BECN1-regulated autophagy protein 1, AMBRA1, AMRA1
    UniProt
    Q9C0C7
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