trace amine-associated receptor (TAAR8) (C-Term) antibody

Antigen: trace amine-associated receptor (TAAR8)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350076

Additional Information

Immunogen: A synthetic peptide as a part of mouse and rat TAAR8a, b, c conjugated to immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Description: FUNCTION: Orphan receptor. Could be a receptor fortrace amines.trace amines are biogenic amines present in very low levels in mammalian tissues. Although sometrace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Also known as: Taar8a, Gm230, Ta11, Trar5, Gm1149, Ta7, Ta10,trace amine-associated receptor 8b, Taar8b,trace amine-associated receptor 8c, Taar8c, TAA8A_RAT, Q923X9,trace amine receptor 11, TaR-11, Tar11, Trar11,trace amine receptor 7, TaR-7, Taar8b, Tar7, Trar7,trace amine receptor 10, TaR-10, Taar8c, Trar10.

Specificity: Appears to be specific for TAAR8a, b, c.

Application Details

Application Notes: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Borowsky, Adham, Jones et al.: "Trace amines: identification of a family of mammalian G protein-coupled receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 8966-71, 2001 (PubMed).

Lindemann, Ebeling, Kratochwil et al.: "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors." in: Genomics, Vol. 85, Issue 3, pp. 372-85, 2005 (PubMed).

Fleischer, Schwarzenbacher, Breer: "Expression of trace amine-associated receptors in the Grueneberg ganglion." in: Chemical senses, Vol. 32, Issue 6, pp. 623-31, 2007 (PubMed).