ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) (C-Term) antibody

Antigen: ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5)

Synonyms: ASP, APG5, APG5L, hAPG5, APG5-LIKE, apg5l

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Fruit Fly (Drosophila melanogaster)

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350083

Additional Information

Alternative name: autophagy protein 5 (ATG5, ASP, APG5, APG5L)

UniProt: Q9W3R7

Immunogen: A synthetic peptide from the c-terminal of drosophila autophagy protein 5 (ATG5, ASP, APG5, APG5L) conjugated to an immunogenic carrier protein has been used as the immunogen.

Format: Lyophilized

Description: ATG5 is an important element forautophagy and may also play an important role in the apoptotic process. Following conjugation to ATG12, the conjugate participates in the formation of autophagosome. While the mRNA is ubiquitously transcribed its expression is highly upregulated in apoptotic cells. Also known as: APG5-like, ATG5, ASP, APG5, APG5L, apoptosis-specific protein.

Specificity: Appears to be specific for ATG5.

Application Details

Application Notes: IHC, WB. Use at a dilution of 1:300 to 1: 2000. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Research Area: Autophagy

Restrictions: For Research Use only

Publications

Adams, Celniker, Holt et al.: "The genome sequence of Drosophila melanogaster." in: Science (New York, N.Y.), Vol. 287, Issue 5461, pp. 2185-95, 2000 (PubMed).

Scott, Schuldiner, Neufeld: "Role and regulation of starvation-induced autophagy in the Drosophila fat body." in: Developmental cell, Vol. 7, Issue 2, pp. 167-78, 2004 (PubMed).