ATG5 antibody (ATG5 Autophagy Related 5 Homolog (S. Cerevisiae)) (N-Term)

Details for Product anti-ATG5 Antibody No. ABIN350084, Supplier: Log in to see
Antigen
  • APG5
  • APG5-LIKE
  • APG5L
  • ASP
  • hAPG5
  • ATG5
  • CG1643
  • DmAtg5
  • Dmel\\CG1643
  • atg5
  • 2010107M05Rik
  • 3110067M24Rik
  • AW319544
  • Apg5l
  • Atg5l
  • C88337
  • Paddy
  • apg5l
  • zgc:100934
  • ATATG5
  • AUTOPHAGY 5
  • MKP11.20
  • MKP11_20
  • autophagy related 5
  • Autophagy-specific gene 5
  • ATG5 autophagy related 5 homolog (S. cerevisiae)
  • APG5 autophagy 5-like
  • similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12
  • autophagy protein 5
  • ATG5
  • Atg5
  • atg5
  • LOC100227318
  • LOC100342807
  • APG5
Alternatives
anti-Fruit Fly (Drosophila melanogaster) ATG5 antibody for Immunohistochemistry
Epitope
N-Term
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31
22
15
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11
8
8
7
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3
3
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2
1
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Reactivity
Fruit Fly (Drosophila melanogaster)
276
121
90
37
33
22
20
12
12
10
8
6
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5
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4
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2
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Host
Rabbit
212
49
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11
2
Clonality
Polyclonal
Conjugate
This ATG5 antibody is un-conjugated
12
12
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Application
Immunohistochemistry (IHC), Western Blotting (WB)
224
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71
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40
13
12
6
5
3
2
2
1
1
1
Options
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Immunogen A synthetic peptide from the n-terminal of drosophila ATG5 conjugated to an immunogenic carrier protein has been used as the antigen.
Specificity Specific for ATG5.
Purification Whole serum
Alternative Name ATG5 (ATG5 Antibody Abstract)
Background ATG5 is an important element forautophagy and may also play an important role in the apoptotic process. Following conjugation to ATG12, the conjugate participates in the formation of autophagosome. While the mRNA is ubiquitously transcribed its expression is highly upregulated in apoptotic cells. Also known as: APG5-like, ATG5, ASP, APG5, APG5L, hAPG5, apoptosis-specific protein.
Pathways Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
Application Notes Use at a dilution of 1:300 to 1: 2000.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Scott, Schuldiner, Neufeld: "Role and regulation of starvation-induced autophagy in the Drosophila fat body." in: Developmental cell, Vol. 7, Issue 2, pp. 167-78, 2004 (PubMed).

Adams, Celniker, Holt, Evans, Gocayne, Amanatides, Scherer, Li, Hoskins, Galle, George, Lewis, Richards, Ashburner, Henderson, Sutton, Wortman, Yandell, Zhang, Chen, Brandon, Rogers, Blazej, Champe, Pfeiffer, Wan, Doyle, Baxter, Helt, Nelson, Gabor, Abril: "The genome sequence of Drosophila melanogaster." in: Science (New York, N.Y.), Vol. 287, Issue 5461, pp. 2185-95, 2000 (PubMed).