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Autophagy Related 10 (ATG10) antibody
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
|4 references available|
|Quantity||150 µl (Variants)|
|Price||454.67 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 7 to 8 Business Days|
|Alternative name||autophagy-related protein 10 (ATG10, APG10)|
|Immunogen||A synthetic peptide as a part of human autophagy-related protein 10 (ATG10, APG10) conjugated to immunogenic carrier protein has been used as the immunogen.|
|Description||Autophagocytosis is a starvation-induced process responsible for transport of cytoplasmic proteins to the vacuole. FUNCTION: Plays a role inautophagy. ATG12-conjugating enzyme (E2-like enzyme), likely serves as an ATG5-recognition molecule. SUBUNIT: Interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. Also able to directly interact either with ATG5 or ATG7. SUBCELLULAR LOCATION: Cytoplasm. Also known as: PP12616, APG10L, APG10-like, APG10, APG10L, pp12616, FLJ13954, DKFZP586I0418, ATG10autophagy related 10 homolog (S. cerevisiae).|
|Specificity||Appears to be specific for ATG10.|
|Application Notes||IHC, WB. Use at a dilution of 1:100 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.|
|Storage||Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.|
|Restrictions||For Research Use only|
Mizushima, Yoshimori, Ohsumi: "Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method." in: FEBS letters, Vol. 532, Issue 3, pp. 450-4, 2002 (PubMed).
Wiemann, Arlt, Huber et al.: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, 2004 (PubMed).
Wan, Gong, Qin et al.: "Large-scale cDNA transfection screening for genes related to cancer development and progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 44, pp. 15724-9, 2004 (PubMed).
Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).
|Hosts||Rabbit (34), Sheep (3)|
|Reactivities||Human (36), Mouse (Murine) (24), Rat (Rattus) (24), Cow (Bovine) (19), Dog (Canine) (1)|
|Applications||Western Blotting (WB) (20), Immunofluorescence (IF) (16), ELISA (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunohistochemistry (IHC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Fixed) (IHC (fx)) (2), Immunoelectron Microscopy (IEM) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)|
|Epitopes||C-Term (4), AA 1-50 (1), AA 173-188 (1), C-Term,Ser116 (1)|