Dr ATG9 (Internal Region) antibody

Details for Product No. ABIN350102, Supplier: Log in to see
Internal Region
Fruit Fly (Drosophila melanogaster)
Immunohistochemistry (IHC), Western Blotting (WB)
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Immunogen A synthetic peptide from an internal region of drosophila ATG9 conjugated to an immunogenic carrier protein has been used as the antigen.
Specificity Specific for ATG9B.
Purification Whole serum
Background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels ofautophagy have been described in some malignant tumors, and a role forautophagy in controlling the unregulated cell growth linked to cancer has been proposed.
Function: Plays a role inautophagy.
Subcellular location: Cytoplasmic vesicle, autophagosome membrane, Multi-pass membrane protein. Also known as: ATG9,autophagy-related protein 9, APG9-like.
Application Notes Use at a dilution of 1 : 200 to 1 : 2000.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Ranz, Maurin, Chan, von Grotthuss, Hillier, Roote, Ashburner, Bergman: "Principles of genome evolution in the Drosophila melanogaster species group." in: PLoS biology, Vol. 5, Issue 6, pp. e152, 2007 (PubMed).

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