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Autophagy Related 9B (ATG9B) antibody

Details for Product No. ABIN350103, Supplier: Log in to see
Antigen
  • APG9L2
  • NOS3AS
  • SONE
  • Apg912
  • Apg9l2
  • Apgdc2
  • Gm574
  • Nos3as
  • eONE
  • sONE
  • RGD1560887
Reactivity
Rat (Rattus)
58
25
25
Host
Rabbit
58
1
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
47
30
22
11
10
9
5
3
2
1
1
Supplier
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Immunogen A synthetic peptide from rat autophagy-related protein 9B (ATG9B, APG9L2) conjugated to an immunogenic carrier protein has been used as the antigen.
Specificity Specific for ATG9B.
Purification Whole serum
Alternative Name ATG9B (ATG9B Antibody Abstract)
Background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels ofautophagy have been described in some malignant tumors, and a role forautophagy in controlling the unregulated cell growth linked to cancer has been proposed.
Function: Plays a role inautophagy.
Subcellular location: Cytoplasmic vesicle, autophagosome membrane, Multi-pass membrane protein.
Tissue specificity: Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial. INDUCTION: By hypoxia, leading to inhibit NOS3 expression. Also known as: ATG9B,autophagy-related protein 9B, APG9-like 2, Nitric oxide synthase 3-overlapping antisense gene protein, Protein sONE, APG9L2, NOS3AS, SONE.
Research Area Cancer, Autophagy
Application Notes Use at a dilution of 1 : 200 to 1 : 2000.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Florea, Di Francesco, Miller et al.: "Gene and alternative splicing annotation with AIR." in: Genome research, Vol. 15, Issue 1, pp. 54-66, 2005 (PubMed).