ATG9 Autophagy Related 9 Homolog B (S. Cerevisiae) (ATG9B) (N-Term) antibody

Antigen: ATG9 Autophagy Related 9 Homolog B (S. Cerevisiae) (ATG9B)

Synonyms: eONE, sONE, Gm574, Apg912, Apg9l2, Apgdc2, Nos3as, SONE, APG9L2, NOS3AS, RGD1560887, zgc:158872

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350106

Additional Information

Alternative name: autophagy-related protein 9B (ATG9B, APG9L2) (n-terminal region)

Swiss-Prot: Q6EBV9

Immunogen: A synthetic peptide as a part of mouse autophagy-related protein 9B (ATG9B, APG9L2, NOS3AS) conjugated to an immunogenic carrier protein has been used as the immunogen.

Format: Lyophilized

Description: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels ofautophagy have been described in some malignant tumors, and a role forautophagy in controlling the unregulated cell growth linked to cancer has been proposed. FUNCTION: Plays a role inautophagy. SUBCELLULAR LOCATION: Cytoplasmic vesicle, autophagosome membrane, Multi-pass membrane protein. TISSUE SPECIFICITY: Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial. INDUCTION: By hypoxia, leading to inhibit NOS3 expression. Also known as: ATG9B,autophagy-related protein 9B, APG9-like 2, Nitric oxide synthase 3-overlapping antisense gene protein, Protein sONE, APG9L2, NOS3AS, SONE.

Specificity: Appears to be specific for ATG9B.

Application Details

Application Notes: IHC, WB. Use at a dilution of 1 : 200 to 1 : 2000. The optimal dilution should be determined by the end user.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Research Area: Autophagy

Restrictions: For Research Use only

Publications

Publications: Florea, Di Francesco, Miller et al.: "Gene and alternative splicing annotation with AIR." in: Genome research, Vol. 15, Issue 1, pp. 54-66, 2005 (PubMed).