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Details for Product No. ABIN350119

Beta, Gamma, kappa Actin (ACTB, ACTG, ACTK) (C-Term) antibody

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Antigen
Epitope
»Alternatives C-Term
Host
»Alternatives Sheep
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350119
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal of human beta, gamma, kappa Actin (ACTB, ACTG, ACTK) conjugated to an immunogenic carrier protein was used as the immunogen. The peptide is homologous in many species including rat, mouse, zebra fish and xenopus.
Specificity Appears to be specific for Actin.
Purity whole serum
Background Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subunit: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
Subcellular location: Cytoplasm, cytoskeleton. Also known as: ACTB, ACTG, ACTK.
UniProt P60709
Application Notes IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Erba, Gunning, Kedes: "Nucleotide sequence of the human gamma cytoskeletal actin mRNA: anomalous evolution of vertebrate non-muscle actin genes." in: Nucleic acids research, Vol. 14, Issue 13, pp. 5275-94, 1986 (PubMed).

Gevaert, Goethals, Martens et al.: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003 (PubMed).

Procaccio, Salazar, Ono et al.: "A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia." in: American journal of human genetics, Vol. 78, Issue 6, pp. 947-60, 2006 (PubMed).

Chang, Yang, Lai et al.: "Identification of a novel actin isoform in hepatocellular carcinoma." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 36, Issue 1, pp. 33-9, 2006 (PubMed).

Zahedi, Lewandrowski, Wiesner et al.: "Phosphoproteome of resting human platelets." in: Journal of proteome research, Vol. 7, Issue 2, pp. 526-34, 2008 (PubMed).

Alternatives for antigen "Beta, Gamma, kappa Actin (ACTB, ACTG, ACTK)", type "Antibodies"
Hosts (2), (1)
Applications (3), (3)
Epitopes (3)
Beacon