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Details for Product No. ABIN350122

Brain Expressed, X-Linked 1 (BEX1) antibody

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Antigen
Synonyms AA407839, AU018692, Bex4, Rex3, BEX2, HBEX2, HGR74-h, BEX1
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350122
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide as a part of human Brain-expressed X-linked protein 1 (BEX1, also called BEX2, HBEX2, HGR74-h) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for BEX1 (BEX2).
Purity whole serum
Alternative Name Brain-expressed X-linked protein 1 (BEX1,BEX2)
Background Function: Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states.
Subunit: Interacts with neurotrophin receptor p75NTR/NGFR. Interacts with OMP.
Subcellular location: Nucleus. Cytoplasm. Note: Shuttles between the cytoplasm and the nucleus.
Tissue specificity: Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia. Also known as: BEX1, BEX2, HBEX2, HGR74-h.
UniProt Q9HBH7
Application Notes IHC, WB. A dilution of 1 : 200 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Yang, Xia, Gu et al.: "Cloning and expression pattern of a spermatogenesis-related gene, BEX1, mapped to chromosome Xq22." in: Biochemical genetics, Vol. 40, Issue 1-2, pp. 1-12, 2002 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Quentmeier, Tonelli, Geffers et al.: "Expression of BEX1 in acute myeloid leukemia with MLL rearrangements." in: Leukemia, Vol. 19, Issue 8, pp. 1488-9, 2005 (PubMed).

Alvarez, Zhou, Witta et al.: "Characterization of the Bex gene family in humans, mice, and rats." in: Gene, Vol. 357, Issue 1, pp. 18-28, 2005 (PubMed).

Alternatives for antigen "Brain Expressed, X-Linked 1 (BEX1)", type "Antibodies"
Hosts (18), (4)
Reactivities (21), (13), (12), (12)
Applications (13), (10), (5), (5), (4), (4)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (2), (1), (1), (1), (1)
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