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Details for Product No. ABIN350124

Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) antibody

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Antigen
Synonyms Bex, BEX3, NADE, HGR74, DXS6984E, AL033356, Bex3, DXWsu67e, Gcap27, Nade, WBP5, NGFRAP1
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN350124
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from human Brain-expressed X-linked protein 3 (BEX3, NGFRAP1, NADE) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for BEX3.
Purity whole serum
Alternative Name Brain-expressed X-linked protein 3 (BEX3, NGFRAP1, NADE)
Background Function: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
Subunit: Self-associates. Interacts with 14-3-3 epsilon. Interacts with DIABLO/SMAC. Binds to the DEATH domain of p75NTR/NGFR.
Subcellular location: Nucleus. Cytoplasm. Note: Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.
Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver. Also known as: Protein BEX3, NGFRAP1, p75NTR-associated cell death executor, Nerve growth factor receptor-associated protein 1 (TNFRSF16) associated protein 1, Ovarian granulosa cell 13.0 kDa protein HGR74, BEX3, DXS6984E, NADE, Bex, HGR74, DXS6984E.
UniProt Q00994
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Rapp, Freudenstein, Klaudiny et al.: "Characterization of three abundant mRNAs from human ovarian granulosa cells." in: DNA and cell biology, Vol. 9, Issue 7, pp. 479-85, 1990 (PubMed).

Mukai, Hachiya, Shoji-Hoshino et al.: "NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR." in: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17566-70, 2000 (PubMed).

Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Alvarez, Zhou, Witta et al.: "Characterization of the Bex gene family in humans, mice, and rats." in: Gene, Vol. 357, Issue 1, pp. 18-28, 2005 (PubMed).

Alternatives for antigen "Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1)", type "Antibodies"
Hosts (36), (5), (4)
Reactivities (41), (27), (15), (11), (11), (11)
Applications (34), (18), (11), (9), (7), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (4), (2), (2), (2), (1), (1), (1)
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