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CACHD1 antibody (AA 1120-1170)

CACHD1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN350133
  • Target See all CACHD1 Antibodies
    CACHD1 (Cache Domain Containing 1 (CACHD1))
    Binding Specificity
    • 1
    • 1
    • 1
    AA 1120-1170
    Reactivity
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 5
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 5
    This CACHD1 antibody is un-conjugated
    Application
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    Specific for CACHD1.
    Cross-Reactivity
    Human, Mouse
    Cross-Reactivity (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogen
    A synthetic peptide from AA 1120-1170 of human CACHD1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse.
    Isotype
    IgG
    Top Product
    Discover our top product CACHD1 Primary Antibody
  • Application Notes
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    CACHD1 (Cache Domain Containing 1 (CACHD1))
    Alternative Name
    CACHD1 (CACHD1 Products)
    Synonyms
    CACHD1 antibody, RP4-655E10.1 antibody, 1190007F10Rik antibody, AI852726 antibody, B430218L07Rik antibody, Vwcd1 antibody, mKIAA1573 antibody, RGD1310770 antibody, cache domain containing 1 antibody, VWFA and cache domain-containing protein 1 antibody, CACHD1 antibody, LOC593655 antibody, cachd1 antibody, Cachd1 antibody
    Background
    FUNCTION: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Defects in CACNA2D4 are the cause of retinal cone dystrophy 4 (RCD4). RCD4 is characterized by minimal symptoms except for slowly progressive reduction in visual acuity. Tissue specificity: Predominantly expressed in certain types of endocrine cells. Present in the Paneth cells of the small intestine. Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophiles of the pituitary. Present at low level in some brain regions such as the cerebellum (at protein level). Subcellular location: Membrane, Single-pass type I membrane protein Miscellaneous: In contrast to CACNA2D1 and CACNA2D2, it does not bind gabapentin, an antiepileptic drug.,Alpha-2/delta Subunit,VWFA and cache domain-containing protein 1, Cache domain-containing protein 1
    UniProt
    Q5VU97
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