CACNA1F antibody

Catalog No. ABIN350143

Product Details anti-CACNA1F Antibody

Target: CACNA1F (Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1F antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for CACNA1F.

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from human CACNA1F conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for CACNA1F

Target: CACNA1F (Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F))

Alternative Name: CACNA1F (CACNA1F Products)

Synonyms: AIED antibody, COD3 antibody, COD4 antibody, CORDX antibody, CORDX3 antibody, CSNB2 antibody, CSNB2A antibody, CSNBX2 antibody, Cav1.4 antibody, Cav1.4alpha1 antibody, JM8 antibody, JMC8 antibody, OA2 antibody, CACNA1F antibody, A930034B14 antibody, Sfc17 antibody, nerg1 antibody, nob2 antibody, calcium voltage-gated channel subunit alpha1 F antibody, voltage-dependent L-type calcium channel subunit alpha-1F antibody, calcium channel, voltage-dependent, L type, alpha 1F subunit antibody, calcium channel, voltage-dependent, L type, alpha 1F subunit a antibody, calcium channel, voltage-dependent, alpha 1F subunit antibody, CACNA1F antibody, Cacna1f antibody, LOC465629 antibody, cacna1fb antibody, cacna1fa antibody, cacna1f antibody

Background: Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Subcellular location: Membrane, Multi-pass membrane protein.,Alpha Subunit,Voltage-gated calcium channel subunit alpha Cav1.4, Voltage-dependent L-type calcium channel subunit alpha-1F

UniProt: O60840