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CACNB1 antibody (Calcium Channel, Voltage-Dependent, beta 1 Subunit) (N-Term)

Details for Product anti-CACNB1 Antibody No. ABIN350155, Supplier: Log in to see
Antigen
  • CAB1
  • CACNB1
  • CACNLB1
  • Cchb1
  • Cchlb1
  • CCHLB1
  • zgc:91982
Epitope
N-Term
36
23
16
9
5
4
3
3
2
2
1
1
Reactivity
Mouse (Murine), Rat (Rattus), Human
94
55
38
5
5
5
4
2
1
1
1
Host
Rabbit
65
47
1
Clonality
Polyclonal
Conjugate
This CACNB1 antibody is un-conjugated
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
107
51
38
38
28
22
3
2
1
Supplier
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Immunogen A synthetic peptide from the n-terminal region of mouse CACNB1 (CAB1) conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 98% identity with rat and human sequences.
Specificity Specific for CACNB1.
Purification Whole serum
Alternative Name CACNB1 (CACNB1 Antibody Abstract)
Background Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting
Subcellular location: Cell membrane › sarcolemma, Peripheral membrane protein, Cytoplasmic side Also known as: Voltage-dependent L-type calcium channel subunit beta-1, Calcium channel voltage dependent subunit beta 1, Cacnb1, Cacnlb1, CAB1.
Research Area Signaling, Transporters
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Munton, Tweedie-Cullen, Livingstone-Zatchej, Weinandy, Waidelich, Longo, Gehrig, Potthast, Rutishauser, Gerrits, Panse, Schlapbach, Mansuy: "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 2, pp. 283-93, 2007

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006

Anderson, Altafaj, Zheng, Wang, Delbono, Ronjat, Treves, Zorzato: "The junctional SR protein JP-45 affects the functional expression of the voltage-dependent Ca2+ channel Cav1.1." in: Journal of cell science, Vol. 119, Issue Pt 10, pp. 2145-55, 2006

Trinidad, Specht, Thalhammer, Schoepfer, Burlingame: "Comprehensive identification of phosphorylation sites in postsynaptic density preparations." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 5, pp. 914-22, 2006