Calcium Channel, Voltage-Dependent, gamma Subunit 1 (CACNG1) (N-Term) antibody

Antigen: Calcium Channel, Voltage-Dependent, gamma Subunit 1 (CACNG1)

Synonyms: CACNLG, MGC117703, Cacng, zgc:55364, wu:fb43f02, wu:fi19g08, cacng1, CACNG1, MGC143418

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350162

Additional Information

Alternative name: CACNG1 (CACNLG) (n-terminal region)

Swiss-Prot: Q06432

Immunogen: A synthetic peptide from the n-terminal region of human CACNG1 (CACNLG) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and mouse.

Format: Lyophilized

Description: FUNCTION: This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca2+ channel may function only as a multiple subunit complex. Tissue specificity: Skeletal muscle. Subcellular location: Membrane; Single-pass type I membrane protein Also known as: Voltage-dependent calcium channel gamma-1 subunit, Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma, CACNLG.

Specificity: Appears to be specific for CACNG1.

Application Details

Application Notes: IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Powers, Liu, Hogan et al.: "Molecular characterization of the gene encoding the gamma subunit of the human skeletal muscle 1,4-dihydropyridine-sensitive Ca2+ channel (CACNLG), cDNA sequence, gene structure, and chromosomal location." in: The Journal of biological chemistry, Vol. 268, Issue 13, pp. 9275-9, 1993 (PubMed).

Iles, Segers, Weghuis et al.: "Localization of the gamma-subunit of the skeletal muscle L-type voltage-dependent calcium channel gene (CACNLG) to human chromosome band 17q24 by in situ hybridization and identification of a polymorphic repetitive DNA sequence at the gene locus." in: Cytogenetics and cell genetics, Vol. 64, Issue 3-4, pp. 227-30, 1993 (PubMed).