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CACNG4 antibody (Calcium Channel, Voltage-Dependent, gamma Subunit 4) (Internal Region)

Details for Product anti-CACNG4 Antibody No. ABIN350166, Supplier: Log in to see
Antigen
  • AI413107
  • AW491861
  • CACNG4
Epitope
Internal Region
16
13
11
6
2
1
Reactivity
Human, Rat (Rattus), Mouse (Murine)
37
13
12
3
2
2
2
Host
Rabbit
38
Clonality
Polyclonal
Conjugate
This CACNG4 antibody is un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
33
17
16
3
1
Supplier
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Immunogen A synthetic peptide from the internal region of human CACNG4 conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat, mouse.
Specificity Specific for CACNG4.
Purification Whole serum
Alternative Name CACNG4 (CACNG4 Antibody Abstract)
Background Function: Thought to stabilize the calcium channel in an inactivated (closed) state. Involvement in disease: Candidate gene for a familial infantile convulsive disorder with paroxysomal choreoathetosis.
Subcellular location: Membrane, Single-pass type I membrane protein Also known as: Voltage-dependent calcium channel gamma-4 subunit, Neuronal voltage-gated calcium channel gamma-4 subunit.
Research Area Signaling
Application Notes A dilution of 1: 300 to 1: 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Chu, Robertson, Best: "Calcium channel gamma subunits provide insights into the evolution of this gene family." in: Gene, Vol. 280, Issue 1-2, pp. 37-48, 2001

Burgess, Davis, Gefrides, Noebels: "Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication." in: Genome research, Vol. 9, Issue 12, pp. 1204-13, 2000

Klugbauer, Dai, Specht, Lacinovua, Marais, Bohn, Hofmann: "A family of gamma-like calcium channel subunits." in: FEBS letters, Vol. 470, Issue 2, pp. 189-97, 2000