Calcium Channel, Voltage-Dependent, gamma Subunit 7 (CACNG7) (N-Term) antibody

Antigen: Calcium Channel, Voltage-Dependent, gamma Subunit 7 (CACNG7)

Synonyms: CACNG5, MGC146777

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350170

Additional Information

Alternative name: CACNG7 (n-terminal region)

Swiss-Prot: P62955

Immunogen: A synthetic peptide from the n-terminal region of human CACNG7 conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in mouse and rat.

Format: Lyophilized

Description: FUNCTION: Thought to stabilize the calcium channel in an inactivated (closed) state. Tissue specificity: Widely expressed Subcellular location: Membrane; Single-pass type I membrane protein Also known as: Voltage-dependent calcium channel gamma-7 subunit, Neuronal voltage-gated calcium channel gamma-7 subunit.

Specificity: Appears to be specific for CACNG7.

Application Details

Application Notes: IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Burgess, Gefrides, Foreman et al.: "A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family." in: Genomics, Vol. 71, Issue 3, pp. 339-50, 2001 (PubMed).

Chu, Robertson, Best: "Calcium channel gamma subunits provide insights into the evolution of this gene family." in: Gene, Vol. 280, Issue 1-2, pp. 37-48, 2001 (PubMed).

Moss, Viard, Davies et al.: "The novel product of a five-exon stargazin-related gene abolishes Ca(V)2.2 calcium channel expression." in: The EMBO journal, Vol. 21, Issue 7, pp. 1514-23, 2002 (PubMed).

Wang, Du, Fang et al.: "Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling." in: The EMBO journal, Vol. 25, Issue 21, pp. 5058-70, 2006 (PubMed).