Calcium Channel, Voltage-Dependent, gamma Subunit 8 (CACNG8) (internal) antibody

Antigen: Calcium Channel, Voltage-Dependent, gamma Subunit 8 (CACNG8)

Synonyms: MGC146001

Epitope: internal

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350172

Additional Information

Alternative name: CACNG8 (internal region)

Swiss-Prot: Q8WXS5

Immunogen: A synthetic peptide from the internal region of human CACNG8 conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in mouse and rat.

Format: Lyophilized

Description: FUNCTION: Thought to stabilize the calcium channel in an inactivated (closed) state. Subcellular location: Membrane; Single-pass type I membrane protein Also known as: Voltage-dependent calcium channel gamma-8 subunit, Neuronal voltage-gated calcium channel gamma-8 subunit.

Specificity: Appears to be specific for CACNG8.

Application Details

Application Notes: IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Burgess, Gefrides, Foreman et al.: "A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family." in: Genomics, Vol. 71, Issue 3, pp. 339-50, 2001 (PubMed).

Chu, Robertson, Best: "Calcium channel gamma subunits provide insights into the evolution of this gene family." in: Gene, Vol. 280, Issue 1-2, pp. 37-48, 2001 (PubMed).

Munton, Tweedie-Cullen, Livingstone-Zatchej et al.: "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 2, pp. 283-93, 2007 (PubMed).