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Product Details

anti-cathelicidin antimicrobial peptide (cAMP) (Internal) antibody

Overview

Antigen: Cathelicidin antimicrobial peptide (cAMP)
Clonality: Polyclonal
Application: Immunohistochemistry (IHC), Western Blotting (WB)
Reactivity: Human
Host: Sheep
6 references available 6 references available
Quantity: 500 ug
Price: 363,33 $   (Plus shipping costs and VAT, Invoice in EUR)
Order number: ABIN350182
Availability: Ships within 7 to 10 Business Days
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Additional Information  » anti-cathelicidin antimicrobial peptide (cAMP) (Internal) antibody

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Antigen Cathelicidin antimicrobial peptide (cAMP)
Swiss-Prot P49913
Immunogen A synthetic peptide from the internal part of human Cathelicidin antimicrobial peptide (CAP-18) conjugated to an immunogenic carrier protein has been used as the immunogen.
Reactivity Human
Host Sheep
Clonality Polyclonal
Format Lyophilized
Isotype IgG »Matching secondary antibodies
Description Cathelicidin antimicrobial protein is an antimicrobial protein found in specific granules of polymorphonuclear leukocytes. FUNCTION: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Expressed in bone marrow and testis and neutrophils.
Specificity Appears to be specific for Cathelicidin antimicrobial peptide.

Application Details  » anti-cathelicidin antimicrobial peptide (cAMP) (Internal) antibody

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Application Immunohistochemistry (IHC), Western Blotting (WB)
» Click here to view 3 available protocols!
Application Notes IHC, WB. Use at a concentration of 10-50 ug/ml. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Purity IgG
Storage Maintain the lyophilised/reconstituted antibodies frozen at -20 C for long term storage and refrigerated at 2-8 C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. Shipping Conditions: This item will be shipped to you at ambient temperature in a lyophilised form. Reconstitution: Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material.
Restrictions For Research Use only

Publications  » anti-cathelicidin antimicrobial peptide (cAMP) (Internal) antibody

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Publications Agerberth, Gunne, Odeberg et al.: "FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis." In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 1, pp. 195-9, 1995 (PubMed)

Cowland, Johnsen, Borregaard: "hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules." In: FEBS letters, Vol. 368, Issue 1, pp. 173-6, 1995 (PubMed)

Larrick, Hirata, Balint et al.: "Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein." In: Infection and immunity, Vol. 63, Issue 4, pp. 1291-7, 1995 (PubMed)

Gudmundsson, Agerberth, Odeberg et al.: "The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes." In: European journal of biochemistry / FEBS, Vol. 238, Issue 2, pp. 325-32, 1996 (PubMed)

Larrick, Lee, Ma et al.: "Structural, functional analysis and localization of the human CAP18 gene." In: FEBS letters, Vol. 398, Issue 1, pp. 74-80, 1997 (PubMed)

Bals, Lang, Weiner et al.: "Rhesus monkey (Macaca mulatta) mucosal antimicrobial peptides are close homologues of human molecules." In: Clinical and diagnostic laboratory immunology, Vol. 8, Issue 2, pp. 370-5, 2001 (PubMed)