Cathelicidin Antimicrobial Peptide (cAMP) antibody

Antigen: Cathelicidin Antimicrobial Peptide (cAMP)

Synonyms: LL37, CAP18, CRAMP, HSD26, FALL39, FALL-39, CATH-2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine)

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350190

Additional Information

Alternative name: Cathelin related antimicrobial peptide (Cathelicidin, CAMP, CRAMP)

Swiss-Prot: P51437

Immunogen: A synthetic peptide from mouse Cathelicidin antimicrobial peptide (CAP-18, hCAP-18, antibacterial protein LL-37, CAMP, CRAMP, FALL39) conjugated to an immunogenic carrier protein has been used as the immunogen.

Format: Lyophilized

Isotype: IgG  (Matching secondary antibodies)

Description: Cathelicidin antimicrobial protein is an antimicrobial protein found in specific granules of polymorphonuclear leukocytes. FUNCTION: Acts as a potent antimicrobial peptide. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Expressed in testis, spleen, stomach, and intestine. Very low expression found in heart, lung and skeletal muscle. No expression in brain, kidney or liver. Also known as: CAMP, FALL39, FALL-39, 18 kDa cationic antimicrobial protein, CAP-18, LL37, CRAMP, HSD26, Cathelin-like protein, CAP18, FALL39, FALL-39, 18 kDa cationic antimicrobial protein.

Specificity: Appears to be specific for Cathelicidin antimicrobial peptide.

Application Details

Application Notes: IHC, WB. Use at a concentration of 10-50 µg/ml. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Purity: IgG

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Popsueva, Zinovjeva, Visser et al.: "A novel murine cathelin-like protein expressed in bone marrow." in: FEBS letters, Vol. 391, Issue 1-2, pp. 5-8, 1996 (PubMed).

Gallo, Kim, Bernfield et al.: "Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse." in: The Journal of biological chemistry, Vol. 272, Issue 20, pp. 13088-93, 1997 (PubMed).