Cathelicidin Antimicrobial Peptide (cAMP) antibody

Antigen: Cathelicidin Antimicrobial Peptide (cAMP)

Synonyms: LL37, CAP18, CRAMP, HSD26, FALL39, FALL-39, CATH-2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Fish

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN350191

Additional Information

Alternative name: fishCathelicidin antimicrobial peptide (CAP-18)

Swiss-Prot: Q71MD7

Immunogen: A synthetic peptide from Myxine glutinosa Cathelicidin antimicrobial peptide (CAP-18, hCAP-18, antibacterial protein LL-37, CAMP, CRAMP) conjugated to an immunogenic carrier protein has been used as the immunogen.

Format: Lyophilized

Description: Cathelicidin antimicrobial protein is an antimicrobial protein found in specific granules of polymorphonuclear leukocytes. FUNCTION: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. SUBCELLULAR LOCATION: Secreted. Also known as: CAMP, CAP18, FALL39, FALL-39, 18 kDa cationic antimicrobial protein, CAP-18, LL37, CRAMP, HSD26.

Specificity: Appears to be specific for Cathelicidin antimicrobial peptide.

Application Details

Application Notes: IHC, WB. Use at a dilution of 1:100 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Purity: whole serum

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Publications: Uzzell, Stolzenberg, Shinnar et al.: "Hagfish intestinal antimicrobial peptides are ancient cathelicidins." in: Peptides, Vol. 24, Issue 11, pp. 1655-67, 2004 (PubMed).