Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN350204

C-Fos antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms D12Rfj1, c-fos, cFos, C-FOS
Reactivity
»Alternatives Human, Rat (Rattus), Mouse (Murine), Hamster, Cat (Feline)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 7 references available
Catalog no. ABIN350204
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from human cFos protein conjugated to an immunogenic carrier protein has been used as the immunogen. The peptide is homologous in many other species including rat, mouse, hamster and cat.
Specificity Appears to be specific for cFOS.
Purity whole serum
Alternative Name cFos (c-fos)
Background Function: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Subunit: Heterodimer. Interacts with DSIPI, this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB
Subcellular location: Nucleus. Also known as: Proto-oncogene protein cFOS, c-Fos.
UniProt P01100
Application Notes IHC, WB. Use at a dilution of 1 : 400 to 1 : 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Roux, Verrier, Klein et al.: "Retrovirus-mediated gene transfer of a human c-fos cDNA into mouse bone marrow stromal cells." in: Oncogene, Vol. 6, Issue 11, pp. 2155-60, 1991 (PubMed).

Nakabeppu, Nathans: "The basic region of Fos mediates specific DNA binding." in: The EMBO journal, Vol. 8, Issue 12, pp. 3833-41, 1990 (PubMed).

Hai, Liu, Coukos et al.: "Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers." in: Genes & development, Vol. 3, Issue 12B, pp. 2083-90, 1990 (PubMed).

van Straaten, Mueller, Curran et al.: "Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 80, Issue 11, pp. 3183-7, 1983 (PubMed).

Glover, Harrison: "Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA." in: Nature, Vol. 373, Issue 6511, pp. 257-61, 1995 (PubMed).

Heilig, Eckenberg, Petit et al.: "The DNA sequence and analysis of human chromosome 14." in: Nature, Vol. 421, Issue 6923, pp. 601-7, 2003 (PubMed).

Vasilescu, Zweitzig, Denis et al.: "The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells." in: Journal of proteome research, Vol. 6, Issue 1, pp. 298-305, 2007 (PubMed).

Alternatives for antigen "C-Fos", type "Antibodies"
Hosts (237), (39), (16), (3), (3)
Reactivities (263), (166), (156), (54), (43), (31), (25), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (201), (129), (70), (58), (56), (15), (14), (11), (8), (7), (7), (3), (3), (2), (1), (1), (1), (1)
Conjugates (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (1), (1)
Epitopes (30), (20), (20), (18), (17), (16), (16), (15), (6), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Beacon