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c-FOS antibody

c-Fos Reactivity: Human WB, IHC Host: Sheep Polyclonal unconjugated
Catalog No. ABIN350206
  • Target See all c-FOS (c-Fos) Antibodies
    c-FOS (c-Fos) (c-Fos)
    Reactivity
    • 247
    • 155
    • 136
    • 13
    • 12
    • 11
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Human
    Host
    • 201
    • 73
    • 7
    • 1
    Sheep
    Clonality
    • 197
    • 84
    Polyclonal
    Conjugate
    • 112
    • 17
    • 15
    • 15
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    This c-FOS antibody is un-conjugated
    Application
    • 241
    • 80
    • 80
    • 77
    • 63
    • 40
    • 34
    • 26
    • 13
    • 13
    • 12
    • 6
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    Specific for cFos.
    Cross-Reactivity
    Human, Marmoset, Mouse, Rat
    Cross-Reactivity (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogen
    A synthetic peptide from human c Fos protein conjugated to blue carrier protein has been used as the antigen.
    Isotype
    IgG
    Top Product
    Discover our top product c-Fos Primary Antibody
  • Application Notes
    IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    c-FOS (c-Fos) (c-Fos)
    Alternative Name
    c Fos (c-Fos Products)
    Synonyms
    AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
    Background
    FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. SUBUNIT: Heterodimer. Interacts with DSIPI, this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB SUBCELLULAR LOCATION: Nucleus. INDUCTION: C-fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury. SIMILARITY: Belongs to the bZIP family. Fos subfamily SIMILARITY: Contains 1 bZIP domain,Nuclear Signaling,Proto-oncogene protein cFOS
    UniProt
    P01100
    Pathways
    S100 Proteins
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