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Details for Product No. ABIN350220

Chloride Channel, Voltage-Sensitive 6 (CLCN6) (Cytoplasmic Domain) antibody

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Synonyms CLC-6, AI850629
»Alternatives Cytoplasmic Domain
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350220
Quantity 100 µL
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the cytoplasmic domain of human Chloride channel protein 6 (CLCN6) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Appears to be specific for CLCN6.
Purity whole serum
Alternative Name Chloride channel protein 6 (CLCN6)
Background Function: Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter.
Subcellular location: Membrane, Multi-pass membrane protein. Note: Detected in detergent-resistant lipid rafts.
Tissue specificity: Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform C is only detected in kidney. Also known as: ClC-6, CLCN6, CLC6.
UniProt P51797
Application Notes IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Nomura, Nagase, Miyajima et al.: "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 1, Issue 5, pp. 223-9, 1995 (PubMed).

Lamb, Clayton, Liu et al.: "Expression of CLCN voltage-gated chloride channel genes in human blood vessels." in: Journal of molecular and cellular cardiology, Vol. 31, Issue 3, pp. 657-66, 1999 (PubMed).

Kornak, Boesl, Kubisch: "Complete genomic structure of the CLCN6 and CLCN7 putative chloride channel genes(1)." in: Biochimica et biophysica acta, Vol. 1447, Issue 1, pp. 100-6, 1999 (PubMed).

Nakajima, Okazaki, Yamakawa et al.: "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 9, Issue 3, pp. 99-106, 2002 (PubMed).

Gregory, Barlow, McLay et al.: "The DNA sequence and biological annotation of human chromosome 1." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 (PubMed).

Alternatives for antigen "Chloride Channel, Voltage-Sensitive 6 (CLCN6)", type "Antibodies"
Hosts (11), (2)
Reactivities (11), (7), (5), (1), (1), (1), (1)
Applications (13), (8), (2)
Epitopes (3), (2), (1), (1)